陈德宇

发布日期:2016-06-13    来源:阜阳师范学院生命科学学院     浏览次数:

陈德宇

职称:教授

研究方向:

(1)生殖生物学

(2)发育生物学

电话:18269992453

电子信箱:chendeyu7104@aliyun.com

个人简历:

2002.9-2005.6就读于南京师范大学生命科学院动物学专业,获理学博士学位;

2003.1-2005.6于南京军区南京总医院生殖遗传中心完成博士课题,课题名称为:前列腺素D合成酶的基础及应用研究;

2005.7-2007.3于阜阳师范学院生物系任副教授,从事《分子生物学》和《细胞生物学》的教学工作;

2007.3- 2009.9工作于汕头大学医学院博士后流动站(生殖医学研究中心),主要从事精子运动机制的研究和抗精液抗体作为阴道内杀精子剂的实验研究工作以及《医学遗传学》和《医学细胞生物学》的教学工作。

2009.9- 2014.7阜阳师范学院教授,阜阳师范学院科研处副处长,并从事动物学相关的科研与教学工作。

2012.9-2013.9 中国科学技术大学访问学者。

2014.7- 阜阳师范学院教授,《阜阳师范学院学报(自然科学版)》主编。

主持的研究项目:

1. 国家自然科学基金, miR-122-5p介导的occludin对支持细胞间紧密连接的调控机制研究;

2. 省高校自然科学重大、重点研究项目, miR-326介导的mTOR通路对支持细胞细胞骨架的调控机制研究;

3. 校地合作横向科研项目,无架瓜萎技术在产业扶贫中的推广与应用

专利:

1.狐狸X精子分离方法.申请号: 201510388072.2(公开(公告)号: CN104962513A;IPC分类号:C12N5/076 .

2.狐狸精液稀释液.申请号: 201510388030.9,公开(公告)号: CN105010306A,IPC分类号:A01N1/02

奖励:

1.精子数量及精子活力的调控机制及其在避孕中的应用研究.安徽省科技进步三等奖,2015;

2. In vitro and in vivo studies evaluating antisemen antibodies as a potential spermicidal agent in hamsters.广东省科学技术协会第二届南粤科技创新优秀论文三等奖,2010;

3. Different expression of lipocalin-type prostaglandin D synthase in rat epididymidis.安徽省第七届自然科学优秀论文二等奖,2013;

4.“阜阳市第七批专业技术拔尖人才”称号,2015;

5. “阜阳师范学院优秀科技工作者”称号, 2014.

代表性论文:

1) Zhu Maoying, Cheng Lifang, Ji Yuntao, Liu Wuyi andChen De-Yu(通讯作者).Correlation analysis of miR-122-5p and occludin with sperm density in oligospermia patients sperm. Clinical Laboratory (In press).

2) Wuyi Liu and Chen De-Yu. Phylogeny, Functional Annotation, and Protein Interaction Network Analyses of the Xenopus tropicalis Basic Helix-Loop-Helix Transcription Factors. BioMed Research International.Volume 2013 (2013), Article ID 145037, 15 pages.http://dx.doi.org/10.1155/2013/145037.

3) Yuntao Ji,Chen De-Yu, Shuanglin Jiang and Changqing Qu. Effect of fasudil hydrochloride on the post-thaw viability of cryopreserved procine adipose-derived stem cells. CryoLetters,2014, 35 (5), 356-360.

4) Chen De-Yu, Li-Min Liu, Dong-Qing Xie,Xu lan, Tian-Hua Huang.In vitro and in vivo studies evaluating antisemenantibodiesas a potential spermicidal agent in hamsters.Fertility and sterility.2009,92,(3):1116-1123.

5) Chen De-Yu, Li-Min Liu, Sheng-Jie Liu, Mao-Ying Zhu, Lan Xu, Tian-Hua Huang. Single-chain antibody against human lipocalin-type prostaglandin D synthase: construction, expression, purification, and activity assay.Biochemistry (Mosco).2008, 73(6):702-710.

6) Chen De-yu, Zhu Mao-ying, Cui Ya-dong, Huang Tian-hua. Relationship between Contents of Lipocalin-Type Prostaglandin D Synthase on the Surface of Infertility Sperm and in Seminal Plasma.Biochemistry (Mosco), 2007, 72(2):255-259.

7) Chen De-yu, Liu Sheng-jie, Zhu Mao-ying, Cui Ya-dong,Li Wen-yong,Huang Yu-feng. Different expression of lipocalin-type prostaglandin D synthase in rat epididymidis.Animal reproduction science,2007,98(3-4):302-310.

8) Chen De-yu, Wang Jun-Jun, Huang Yu-Feng, Zhou Kai-Ya.Relationship between lipocalin-type prostaglandin D synthase and α-glucosidase in azoospermia seminal plasma.Clinica chimica acta, 2005, 354(1-2):69-76.