谢鑫 cpu_xiexin@163.com
2014/09-2020/08，中国药科大学，博士研究生（硕博连读）
2020/08-至今，阜阳师范大学，生物与食品工程学院，讲师
研究方向
1. 环境与肿瘤发生发展分子机制
2. 自身免疫性疾病发病分子机制
主持或参加科研项目（课题）
1. 项目名称：低氧环境下卡格列净调控GLUT1-AMAP-HIF-1α代谢信号轴增加胰腺癌免疫应答的机制研究，安徽省高等学校自然科学研究项目，KJ2020A0538，主持，在研
2. 项目名称：Ⅰ类新药抗真菌多肽PL-18和抗耐药菌多肽Cbf-14临床前研究，十三五国家“新药创制”科技重大专项，参与，在研
3. 项目名称：创新药物研究开发--抗肿瘤新药海胆黄多糖（Ⅰ类）的临床前研究，十二五国家“新药创制”科技重大专项，参与，结题
4. 项目名称：黄芩苷诱导肿瘤细胞老化参与大肠癌治疗新机制研究，国家自然科学基金，81472233，参与，结题
代表性研究成果和学术奖励情况
1. Lingman Ma1, Xin Xie1, Hanhan Liu, Ya Huang, Haomin Wu, Meiling Jiang, Pengfei Xu, Xinyue Ye, Changlin Zhou*. Potent antibacterial activity of MSI-1 derived from the magainin 2 peptide against drug-resistant bacteria. Theranostics, 2020, 10(3):1373-1390
2. Xin Xie1, Wen Shen1, Yiran Zhou, Lingman Ma, Duiyue Xu, Jialu Ding, Liangyuan He, Baiyong Shen, Changlin Zhou. Characterization of a polysaccharide from Eupolyphaga sinensis walker and its effective antitumor activity via lymphocyte activation. International Journal of Biological Macromolecules, 2020, 162:31-42
3. Xin Xie1, Lingman Ma1, Yiran Zhou, Wen Shen, Duiyue Xu, Jie Dou, Baiyong Shen, Changlin Zhou*. Polysaccharide enhanced NK cell cytotoxicity against pancreatic cancer via TLR4/MAPKs/NF-κB pathway in vitro/vivo. Carbohydrate Polymers, 2019, 225:115223
4. Duiyue Xu1, Yiran Zhou1, Xin Xie, Lingman Ma, Jialu Ding, Shuyang Pang, Baiyong Shen*, Changlin Zhou*. Inhibitory effects of canagliflozin on pancreatic cancer are mediated via the downregulation of glucose transporter-1 and lactate dehydrogenase A [J]. International Journal of Oncology, 2020, 57:1223-1233.
5. Qian Yu1, Minda Zhang1, Qidi Ying, Xin Xie, Shuwen Tong, Qing Wei, Zhaoshi Bai*, Lingman Ma*. Decrease of AIM2 mediated by luteolin contributes to non-small cell lung cancer treatment [J]. Cell Death & Disease, 2019, 10:218
